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DoD Peer Reviewed Orthopaedic Clinical Trial Development Award

Post Date

April 30th 2014

Application Due Date

October 24th 2014

Funding Opportunity Number

W81XWH-14-PRORP-CTDA

CFDA Number(s)

12.420

Funding Instrument Type(s)

Cooperative Agreement
Grant

Funding Activity Categories

Science and Technology and other Research and Development

Number of Awards

4

Eligibility Categories

Unrestricted

Funding

  • Estimated Total Funding:

    $1200000

  • Award Range:

    $None - $None

Grant Description

The PRORP CTDA is intended to support the planning and development activities necessary to support preparation for clinical trials with the potential to have a significant impact on Warfighters and Veterans recovering from traumatic orthopaedic injuries. The clinical trials proposed may be focused on any aspect of treatment of orthopaedic injuries that addresses at least one of the FY14 PRORP CTDA Focus Areas, including the evaluation of promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies. All applications are required to justify the relevance of the proposed project to military and/or Veteran populations affected by combat-related orthopaedic injury. Applicants addressing non-battle orthopaedic injuries must articulate how the trial has the potential to impact unit readiness and return-to-duty/work rates. Collaboration with military or VA researchers and clinicians, and inclusion of active duty military or Veteran participants as all or a portion of the future study population, is highly encouraged. Applications are being solicited in the following focus areas: Identify and reduce the secondary health effects (e.g., joint contracture, obesity, metabolic syndrome, poor bone health) that follow reduced mobility from traumatic neuromusculoskeletal injury; Strategies to inhibit neuromas at surgical/amputation sites; The application of novel and/or innovative technologies and materials in prosthetic and orthotic device development; Research toward osseointegration of upper extremity prostheses; Research on treatment of non-battle orthopaedic injuries that impact unit readiness and reflect historical return to work rates less than 50% or longer than 6 months; Physical or occupational therapy (PT/OT) interventions to establish optimal rehabilitation and examine the comparative effectiveness of different PT/OT regimes; Clinical trials to restore function after volumetric muscle loss.

Contact Information

  • Agency

    Department of Defense

  • Office:

    Dept. of the Army -- USAMRAA

  • Agency Contact:

    301-682-5507; help@eBRAP.org

  • Agency Mailing Address:

    CDMRP Help Desk

  • Agency Email Address:

    help@eBRAP.org


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