Production Of Human Proteins To Be Used For Generating Affinity Reagents (U01)

Post Date

February 26th 2010

Application Due Date

April 26th 2010

Funding Opportunity Number

RFA-RM-10-007

CFDA Number(s)

93.310

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Number of Awards

1

Eligibility Categories

State Governments
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $1000000

• Award Range:

  $None - $600000

Grant Description

Purpose. This FOA is the first component of a pilot program organized under the NIH Common Fund Protein Capture Initiative to examine the feasibility and value of generating a community resource of high quality, renewable affinity reagents for all human proteins. This specific FOA topic is focused on the production of proteins or peptides for the purpose of generating monoclonal antibodies that can be used in immunoprecipitation studies, and potentially for other affinity reagents, as well as broader uses by the scientific community and others. Thus, the FOA solicits projects that will provide the targeted proteins, peptides or other immunogens to other components of the pilot program (including a component that will generate monoclonal antibodies, to be solicited in FY2011), as well as to the wider community in the form of a renewable resource, e.g., clones or transfected cell lines.This FOA will prioritize human transcription factors as an initial set of targets. Mechanism of Support. This FOA will utilize the U01 Research Project Cooperative Agreement activity code. Funds Available and Anticipated Number of Awards..We expect to fund a single three year award in FY2010. Total funds available for the program are $1M, for each of three years.. Budget and Project Period.Applications should propose no more than $600,000 in direct costs per year over a period of no more than three years.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-10-007.html