Advanced Technologies for Detection of Perturbation-Induced Cellular Signatures (U01)

Post Date

August 6th 2010

Application Due Date

February 22nd 2011

Funding Opportunity Number

RFA-RM-10-004

CFDA Number(s)

93.310

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Number of Awards

4

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $5600000

• Award Range:

  $None - $500000

Grant Description

Purpose. This FOA encourages grant applications that propose to develop or substantially adapt technologies and methodologies designed to significantly improve the functionality, quality, scope, and/or throughput of perturbation-induced cellular signature data generation. The technologies generated through this FOA are anticipated to accelerate the rate of data generation and the range of signatures that can be identified and characterized by large scale high-throughput perturbation-induced signature collection efforts like The Library of Integrated Network-Based Cellular Signatures (LINCS). Mechanism of Support. This FOA will utilize the U01 award mechanism. It is intended to complement RFA-RM-10-003, Large Scale Production of Perturbagen-Induced Cellular Signatures (U54),that establishes data production efforts to systematize approaches for identifying mechanism-based associations among the effects of disparate biological perturbations and a knowledge base to study functional relationships among the responding cellular components. Released in parallel with this FOA is RFA-RM-10-005, Computational Tool Development and Integrative Data Analysis for LINCS (U01), which seeks to develop innovative computational tools and approaches for the integrative analysis of multiple types of data generated within LINCS. Funds Available and Anticipated Number of Awards. We expect to fund up to four awards in FY2011. Total funds available for the initiative are $2.8M in each of FY2011 and FY2012, contingent upon receiving scientifically meritorious proposals. For this funding opportunity, budgets up to $500,000 direct costs per year and time periods up to two years may be requested.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-10-004.html