Membrane Protein Production for Structure Determination (R01)

Post Date

December 3rd 2009

Application Due Date

February 1st 2010

Funding Opportunity Number

RFA-RM-09-012

CFDA Number(s)

93.310

Funding Instrument Type(s)

Grant

Funding Activity Categories

Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Award Range:

  $None - $None

Grant Description

Purpose. This FOA solicits applications to develop innovative methods for membrane protein production so that the rate of membrane protein structure determination may be enhanced. Methods development for expression, solubilization, stabilization, purification, characterization, crystallization, and isotopic labeling of membrane proteins to enable the determination of their structures by electron microscopic, x-ray diffraction, nuclear magnetic resonance (NMR), mass spectrometry, and other biophysical techniques are emphasized. This FOA is a follow-on to the NIH Roadmap RFA-RM-07-003 with updates and modification of the mechanisms of grant support that are to be used. Mechanism of Support. This FOA will utilize the R01 grant mechanism. Funds Available and Anticipated Number of Awards. The total amount of funding that the NIH expects to award through this announcement is $3-5 million in FY10; the anticipated number of awards is 13-16 awards and this number will depend on the budgets and areas of IC interest of the awards made.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-09-012.html