Clinical and Data Coordinating Center(s) for Parkinsons Disease Biomarkers Identification Network (PD-BIN) (U01)

Post Date

September 24th 2010

Application Due Date

January 18th 2011

Funding Opportunity Number

RFA-NS-11-005

CFDA Number(s)

93.853

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Award Range:

  $None - $None

Grant Description

The NINDS intends to fund a multi-site, multi-project network (Parkinsons Disease Biomarker Identification Network, or PD-BIN) devoted to identifying biological markers for PD risk, onset, and/or progression, in order to facilitate development of disease-modifying treatments. The purpose of this FOA is to solicit linked cooperative agreement (U01) applications for the establishment of a Clinical Coordinating Center (CCC) and a Data Coordinating Center (DCC). The PIs for the DCC and CCC must coordinate their submissions. The CCC will be responsible for the oversight of all aspects of subject recruitment and specimen acquisition, including the management of multiple clinical sites (to be identified by the CCC applicant), enrollment of a core cohort of newly diagnosed patients with PD and matched controls, and accurate collection of all clinical and biological data. The DCC will provide all data management aspects for standardized acquisition, quality control, dissemination and public accessibility. The CCC and DCC must be flexible enough to accommodate and support a wide range of future add-on research projects seeking to utilize and augment the core PD-BIN data. Individual hypothesis-driven studies are not a component of this FOA. It is anticipated that all data and biospecimens acquired will be used to create a publicly available resource for biomarker validation and discovery. The CCC and the DCC will be expected to advance the general scientific goal of identifying and validating useful PD biomarkers.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-11-005.html