Exploratory Studies of Induced Pluripotent Stem (iPS) Cells from Healthy and Mental Health Patient Populations (R21/R33)

Post Date

November 14th 2008

Application Due Date

February 27th 2009

Funding Opportunity Number

RFA-MH-09-130

CFDA Number(s)

93.242

Funding Instrument Type(s)

Grant

Funding Activity Categories

Health

Number of Awards

10

Eligibility Categories

Public and State Controlled Institutions of Higher Education
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) .

Funding

• Estimated Total Funding:

  $2250000

• Award Range:

  $None - $200000

Grant Description

Purpose.This Funding Opportunity Announcement (FOA), issued by the National Institute of Mental Health (NIMH), solicits Exploratory/Developmental Phased Innovation (R21/R33) grant applications from institutions or organizations that propose to generate and characterize induced pluripotent stem (iPS) cells from human control and/or patient populations with cognitive, affective, social, sleep and developmental brain disorders. This can, but does not need to, include disorders in which a genetic linkage has already been inferred. Applications that combine expertise in stem cell biology, cortical development and the clinical study or treatment of mental disorders are strongly encouraged. Responsive applications will place an emphasis on appropriate validation of iPS cells and their derivatives, evaluating the hetero/homogeneity of any cell populations to be screened and use of cellular assays relevant to brain function and mental disorders. Studies involving the acquisition of tissue from new subjects should include provisions to archive and distribute non-induced (e.g., primary) cells. Since studies likely require several areas of expertise, applicants are encouraged to include multiple PIs on the application.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-09-130.html