Heart Failure Clinical Research Network Regional Clinical Centers (U10)

Post Date

June 4th 2010

Application Due Date

December 1st 2010

Funding Opportunity Number

RFA-HL-12-001

CFDA Number(s)

93.837

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $29120000

• Award Range:

  $None - $None

Grant Description

Purpose. The purpose of this solicitation is to request applications for participation in the continuation of the Heart Failure Clinical Research Network as a Regional Clinical Center. A separate solicitation (RFA-HL-12-002) seeks applications for the Coordinating Center. The original network was established to provide a mechanism to expedite clinical research that evaluates strategies to diagnose, manage and treat all forms of heart failure (HF). The renewal program will continue to provide support to develop, coordinate, and conduct multiple collaborative randomized clinical trials (RCTs) to improve HF outcomes. The focus is on small to intermediate-sized concurrent RCTs that can be completed within 2-5 years and the program is not designed to fund large, Phase III definitive studies. Proposed studies should provide clinically relevant pathophysiologic information and move the field of HF treatment forward. Regional Clinical Centers will provide scientific leadership in the collaborative development of the Networks scientific agenda. Regional Clinical Centers may propose a structure that includes geographically or organizationally linked partners or satellites for efficient trial implementation and patient recruitment. The solicitation is open to new and currently participating centers. Mechanism of Support. This FOA will utilize the U10 award mechanism. Funds Available and Anticipated Number of Awards. A total of $29.12 million over 7 years will be available and awards will be made for up to 9 Regional Clinical Centers (RCC). Of this, $4.2 million over 7 years will be awarded for four Clinical Research Skills Development Cores. In addition, RCCs and their satellites will be eligible to receive disbursement of Protocol Funds administered by the Coordinating Center (CC). The total available Protocol Funds for the conduct of clinical trials (including any necessary Core Laboratories) is $16.8 million.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-12-001.html