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PFINDR: Phenotype Finder IN Data Resources: A Tool to Support Cross-study Data Discovery Among NHLBI Genomic Studies (UH2/UH3)

Post Date

June 8th 2010

Application Due Date

September 15th 2010

Funding Opportunity Number

RFA-HL-11-020

CFDA Number(s)

93.233
93.837
93.838
93.839

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

  • Award Range:

    $None - $None

Grant Description

Purpose. This FOA invites applications for projects that propose to develop and apply advanced informatics approaches to categorize phenotypic measures in multiple datasets in data repositories to help researchers identify potentially relevant genomic studies across cardiovascular, lung, blood, and sleep research domains. Mechanism of Support. This FOA will utilize the NIH two-phased Exploratory/Developmental (UH2/UH3) cooperative agreement mechanism. The program will be funded in two phases, as allowed by this mechanism. The initial two-year, milestone-driven pilot phase (UH2) will allow investigators to implement phenotype mappings in their proposed heart, lung, blood and sleep scientific focus area(s) using dbGaP or an equivalent public database. The results of the pilot (UH2) phase will be used to support the scale-up phase (UH3), which will be awarded after administrative review to select the project that has demonstrated the most useful and extensible approach to phenotype mapping. The UH3 phase will apply the approach successfully demonstrated in the UH2 phase to a broader array of heart, lung, blood, and sleep phenotypic variables within dbGaP. The UH2/UH3 application must be submitted as a single application, and applicants should note specific instructions for each phase in this FOA. Funds Available and Anticipated Number of Awards. The total amount of funds available for these awards is $2 million total costs for the pilot phase (UH2) in FY11-12 and $3 million total costs for the UH3 in FY 13-15. Up to two UH2 and one UH3 awards are anticipated from this solicitation. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

Contact Information


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