NHLBI Pediatric Cardiac Genomics Consortium (U01)

Post Date

December 4th 2008

Application Due Date

February 6th 2009

Funding Opportunity Number

RFA-HL-09-003

CFDA Number(s)

93.837

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Eligibility Categories

State Governments
Public and State Controlled Institutions of Higher Education
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Non-domestic (non-U.S.) Entities (Foreign Organizations); Tribally Controlled Colleges and Universities (TCCUs) .

Funding

• Award Range:

  $None - $None

Grant Description

-Purpose. The National Heart, Lung, and Blood Institute (NHLBI) and the Canadian Institutes of Health Research (CIHR) invite applications to participate in a new NHLBI Pediatric Cardiac Genomics Consortium, a cooperative investigative group that will conduct clinical and translational research on the genetic causes of congenital heart disease and genetic contributions to outcome in individuals with congenital heart disease.The purpose of this initiative is to support collaborative genetic and genomic research leading to a comprehensive understanding of the causes and outcomes of congenital heart disease in the human population.The Consortium will consist of up to 6 Research Centers, Cores, and a Steering Committee.Research Center applicants will propose detailed investigation of the genetics and genomics of one or more human cardiac malformations, with the goal of identifying genetic influences on outcome, as well as causative genes.Individual Research Centers will collaborate in recruitment of individuals with congenital heart disease and their families for all Research Center projects.This Consortium is part of a new NHLBI translational program in pediatric cardiovascular disease, which includes the companion NHLBI Cardiac Development Consortium (http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-09-002.html), and Administrative Coordinating Center for both Consortia (http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-09-011.html).These consortia will interact with each other and with the NHLBI Pediatric Heart Network (www.PediatricHeartNetwork.com) to encourage translation of results from basic science to clinical research, and to provide clinical input on pressing needs for basic research. -Mechanism of Support. This FOA will utilize the Research Project Cooperative Agreement (U01) mechanism of support. -Funds Available and Anticipated Number of Awards. The NHLBI intends to commit approximately $1,440,000 total costs for FY2009.The total amount to be awarded for the Pediatric Cardiac Genomics Consortium will be a maximum of $25,440,000 total costs for the six-year project period.It is anticipated that up to 6 research centers will be awarded.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-09-003.html