Centers for Mendelian Genomics (UM1)

Post Date

December 12th 2014

Application Due Date

April 7th 2015

Funding Opportunity Number

RFA-HG-15-002

CFDA Number(s)

93.172

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Funding

• Estimated Total Funding:

  $40000000

• Award Range:

  $None - $5000000

Grant Description

This FOA invites applications for the Centers for Mendelian Genomics Program (CMG Program). With this reissuance, NHGRI intends to achieve the following specific objectives. First, the Program will aim to discover as many genes that bear causal genetic variants ("causal genes") for human Mendelian diseases and non-disease Mendelian traits ("Mendelian conditions") as possible, using genome-wide sequencing and other complementary genomic approaches at the funded centers, and through collaborations with clinical and genetic researchers worldwide. Second, the Program will aim to enhance the chances of success in causal gene discoveries by improving sample solicitation strategies, discovery approaches, study designs, data analysis methods, and costs and efficiency of the discovery pipelines. Third, the Program will aim to enable others to discover more causal genes by disseminating the methods, tools, and other resources that will be developed under this FOA. Finally, the Program will facilitate common interests-based collaborations and avoid unproductive duplication of efforts on causal gene discoveries, through worldwide coordination. At a higher level, NHGRI intends that these activities will lead to insights on what methods, scale, and infrastructure will be necessary to discover all or most of the causal genes for human Mendelian conditions, and bring the field forward toward this goal.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-15-002.html