Mendelian Disorders Genome Centers (U54)

Post Date

December 14th 2010

Application Due Date

March 3rd 2011

Funding Opportunity Number

RFA-HG-10-016

CFDA Number(s)

93.172

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Number of Awards

2

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $10000000

• Award Range:

  $None - $None

Grant Description

This FOA seeks to establish a center or centers that will use genome-wide sequencing and other genomic approaches to discover the genetic variants underlying Mendelian disorders and other health-related Mendelian phenotypes in human. The centers should aim to uncover the genetic basis for as many of these phenotypes as possible with the funds available during the funding period. More generally, NHGRI intends that this effort will provide a foundation for the broader research community to elucidate the genetic basis of all Mendelian disorders, and to that end this FOA has two additional purposes that are outlined below. First, this FOA seeks to establish and refine the most effective and efficient designs, technologies, and analysis methods for elucidating the genetic basis of Mendelian phenotypes. This will necessitate balancing cost, efficiency, and quality. NHGRI expects that the data obtained by the funded projects will help determine the range of tractability of Mendelian phenotypes to state-of-the-art genomic approaches. NHGRI intends that this knowledge will be disseminated to the broader community working on these phenotypes, so that progress towards a comprehensive understanding of the genetic basis of Mendelian disorders will be accelerated.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-10-016.html