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Peripheral Blood Biomarkers of Chronic Traumatic Brain Injury in Human Subjects - SBIR Direct Phase II (R44)

Post Date

June 25th 2014

Application Due Date

August 29th 2014

Funding Opportunity Number

RFA-HD-15-012

CFDA Number(s)

93.865

Funding Instrument Type(s)

Grant

Funding Activity Categories

Health
Income Security and Social Services

Eligibility Categories

Small Businesses

Other Eligible Applicants include the following: Only United States small business concerns (SBCs) are eligible to submit applications for this opportunity. A small business concern is one that, at the time of award of Phase I and Phase II, meets all of the following criteria: 1. Is organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor; 2. Is in the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there must be less than 50 percent participation by foreign business entities in the joint venture; 3.Ф(i) SBIR and STTR.ФBe a concern which is more than 50 percent directly owned and controlled by one or more individuals (who are citizens or permanent resident aliens of the United States), other business concerns (each of which is more than 50 percent directly owned and controlled by individuals who are citizens or permanent resident aliens of the United States), or any combination of these; OR (ii) SBIR-only.ФBe a concern which is more than 50 percent owned by multiple venture capital operating companies, hedge funds, private equity firms, or any combination of these.ФNo single venture capital operating company, hedge fund, or private equity firm may own more than 50 percent of the concern; OR (iii) SBIR and STTR.ФBe a joint venture in which each entity to the joint venture must meet the requirements set forth in paragraph 3 (i) or 3 (ii) of this section. A joint venture that includes one or more concerns that meet the requirements of paragraph (ii) of this section must comply with _ 121.705(b) concerning registration and proposal requirements. 4.ФHas, including its affiliates, not more than 500 employees.

Funding

  • Estimated Total Funding:

    $1500000

  • Award Range:

    $None - $750000

Grant Description

The purpose of this FOA is to support projects that demonstrate the presence of protein biomarkers that are related to brain structure or neurological function in patients in the chronic stages of traumatic brain injury (CBI).The research will provide anatomical evidence for changes in neurological, cognitive or emotional status seen in the years that follow brain trauma, and may serve as surrogate markers for recovery or decline.

Contact Information


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