Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (SBIR [R43])

Post Date

November 6th 2012

Application Due Date

February 14th 2013

Funding Opportunity Number

RFA-ES-13-003

CFDA Number(s)

93.113

Funding Instrument Type(s)

Grant

Funding Activity Categories

Environment
Health

Eligibility Categories

Small Businesses

Funding

• Estimated Total Funding:

  $2500000

• Award Range:

  $None - $225000

Grant Description

This Funding Opportunity Announcement (FOA) solicits Small Business Innovative Research (SBIR) grant applications from small business concerns (SBCs) to develop medium- to high-throughput assays to evaluate the effects of toxicants on pluripotent or induced pluripotent cells with respect to cell differentiation and the resulting differentiated cell populations. The ability to incorporate genetic diversity in these assays would be useful. These assays will provide information on mechanisms of chemically-induced biological activity, help to prioritize chemicals for more extensive toxicological evaluation, support more predictive models of in vivo biological response, and potentially inform on the role of genetic diversity in toxicological effects.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-13-003.html