TaRGET I: Chromatin Structure, Genomics, and Transcriptional Responses to the Environment (R01)
Post Date
August 23rd 2012
Application Due Date
November 19th 2012
Funding Opportunity Number
RFA-ES-12-008
CFDA Number(s)
93.113
93.279
Funding Instrument Type(s)
Grant
Funding Activity Categories
Number of Awards
5
Eligibility Categories
State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Funding
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Estimated Total Funding:
$3000000
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Award Range:
$None - $400000
Grant Description
In order to understand the mechanisms by which toxicants impact gene expression, it is necessary to better understand how exposure affects the proteins and processes upstream of DNA methylation and other epigenetic marks. The NIEHS has made a significant investment in research aimed at identifying epigenetic signatures of exposure, but the mechanistic studies aimed at identifying how these epigenetic marks are established are currently under-represented in our portfolio. The purpose of this FOA is to encourage research applications that will potentially move the field from descriptive and correlative studies to an enhanced mechanistic understanding of how environmental exposures affect the proteins and functional genomic elements involved in establishing and maintaining gene expression patterns and chromatin states.
Contact Information
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Agency
Department of Health and Human Services
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Office:
National Institutes of Health
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Agency Contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV -
Agency Mailing Address:
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
- Agency Email Address:
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More Information:
http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-12-008.html
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