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Engineered Nanomaterials: Linking Physical and Chemical Properties to Biology (U19)

Post Date

November 3rd 2009

Application Due Date

January 22nd 2010

Funding Opportunity Number

RFA-ES-09-011

CFDA Number(s)

93.113

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Environment
Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

  • Estimated Total Funding:

    $5000000

  • Award Range:

    $None - $750000

Grant Description

Purpose. The National Institute of Environmental Health Sciences invites applications that will (1) determine which physical or chemical characteristic of an engineered nanomaterial (ENM), or cluster of characteristics, is integral to ENM-molecular interactions in a cellular process or organ system and (2) relate these findings to potential health effects. NIEHS recognizes that three types of activities need to converge to accomplish this research agenda. The first activity should focus on a detailed understanding of how physical and chemical characteristics of ENMs influence their molecular interactions at the cellular level, while the second activity should determine how the physical and chemical characteristics critical to that interaction are associated with any observed physiological or pathobiological events. The third activity will capitalize on these multidisciplinary efforts through integration of biochemical, molecular, and physiological mechanisms to expand traditional hazard identification and health risk assessment. An extraordinary level of synergy, integration, and potential for advancement of ENM hazard identification and risk assessment is expected. Proposals responsive to this FOA should employ three projects that will examine an overarching research theme through mechanistic studies and in vitro, ex vivo, and in vivo model systems. Grants awarded under this FOA will become part of a consortium that will collaboratively manage the research conducted through the individual grants. Mechanism of Support. This FOA will utilize the U19 grant mechanism Funds Available and Anticipated Number of Awards. The total amount of funding to be committed to this program is $5 million (total costs) per year for 5 years.

Contact Information


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