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Limited Competition for the Continuation of the Diabetes Prevention Program Outcomes Study (DPPOS) Clinical Centers (Collaborative U01)

Post Date

February 6th 2015

Application Due Date

April 9th 2015

Funding Opportunity Number


CFDA Number(s)


Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Food and Nutrition

Number of Awards


Eligibility Categories

Public and State Controlled Institutions of Higher Education
Private Institutions of Higher Education

Other Eligible Applicants include the following: This FOA is limited to the current awardees of the Diabetes Prevention Program Outcomes Study (DPPOS) Clinical Centers.


  • Estimated Total Funding:


  • Award Range:

    $None - $None

Grant Description

The purpose of this Limited Competition Funding Opportunity Announcement (FOA) is to continue follow-up of the Diabetes Prevention Program Outcomes Study (DPPOS) cohort through a collaborative cooperative agreement. The Diabetes Prevention Program (DPP) was a multi-center controlled clinical trial examining the efficacy of treatments to prevent or delay the development of type 2 diabetes in a population at high risk. The DPP demonstrated that either lifestyle change or the drug metformin could reduce the development of type 2 diabetes by 58% and 31%, respectively, compared with placebo. Following the end of DPP, the DPP cohort was enrolled in the DPPOS to determine the long-term effects of the DPP interventions on further diabetes development and microvascular complications. The primary purpose of this FOA is to support the DPPOS clinical centers to continue follow-up of the DPPOS cohort to examine the effectiveness of early metformin treatment on the development of cardiovascular disease and cancer. RFA-DK-15-505 will support continuation of the DPPOS Biostatistics Research Center.

Contact Information

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