Behavioral Pharmacology and Genetics: Translating and Targeting Individual Differences (R03)

Post Date

October 1st 2008

Application Due Date

January 27th 2009

Funding Opportunity Number

RFA-DA-09-016

CFDA Number(s)

93.279

Funding Instrument Type(s)

Grant

Funding Activity Categories

Education
Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $2000000

• Award Range:

  $None - $None

Grant Description

-Purpose.ÊIndividual differences in response to drugs of abuse may confer vulnerability or resistance to drug abuse or the development of addiction. Several lines of evidence indicate that genetic variation contributes to drug abuse and addiction as well as to the propensity to use specific classes of drugs, such as psychostimulants, opiates, marijuana and nicotine.ÊRecently developed genetic methodologies make it possible to better understand drug abuse phenotypes in terms of underlying genetic factors.ÊThis FOA seeks applications that use controlled, human laboratory-based experimental techniques for the measurement of behavior, combined with genetic analyses, to study drug abuse phenotypes and/or endophenotypes, and their relationship to (a) individual differences in response to drugs of abuse; (b) individual differences in the consequences of repeated abuse; or (c) pharmacogenetic differences in response to putative or currently used pharmacotherapeutic agents for treating addiction.ÊResearch in these areas may identify genetic variations that will help define the biochemical mechanisms underlying drug effects and the associated biological and/or behavioral processes responsible for individual differences, and may suggest genetically targeted pharmacotherapeutic approaches for treating addiction. -Mechanism of Support. This FOA will utilize the R03 grant mechanism to support projects including pilot and feasibility studies; small, self-contained research projects; and to foster the establishment of new research collaborations between geneticists and drug abuse researchers. As the R03 is intended to support small research projects that can be carried out in a short period of time with limited resources, it is intended that, with the use of this mechanism, investigators and collaborative research groups will be able to conduct initial pilot and feasibility studies to better position them for a subsequent R01 application.Ê

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-09-016.html