Tumor Microenvironment Network (TMEN) (U54)

Post Date

September 30th 2010

Application Due Date

January 20th 2011

Funding Opportunity Number

RFA-CA-10-021

CFDA Number(s)

93.393
93.394
93.395
93.396
93.397
93.398
93.399

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Education
Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Public and State Controlled Institutions of Higher Education
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Other

Other Eligible Applicants include the following: U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $10450000

• Award Range:

  $None - $700000

Grant Description

Purpose. This Funding Opportunity Announcement (FOA) is designed to promote research on tumor microenvironment with the focus on understanding the role of host stroma in tumorigenesis and responses to treatment. Through this FOA, the National Cancer Institute (NCI) and National Institute of Neurological Disorders and Stroke (NINDS) invite cooperative agreement applications from groups of investigators interested in forming Research Centers serving as components of an interactive NCI Tumor Microenvironment Network (TMEN). The main scientific objectives of TMEN are: 1) to generate a comprehensive understanding of composition of the stroma in normal tissues as well as its roles in tumor initiation, progression, and metastasis; 2) to delineate mechanisms of tumor-stroma interactions in human cancer; and 3) to identify the mechanism(s) by which tumor stroma may affect responses to treatment. In addition to these general NCI priorities, NINDS is particularly interested in research programs relevant to primary brain tumors or peripheral nervous system tumors. TMEN members will be expected to participate in collaborative efforts (to be developed within TMEN) that are directed at: 1) developing resources and reagents critical to the analysis of the tumor microenvironment; 2) developing novel technologies for use in tumor microenvironment research; and 3) outreach activities to facilitate dissemination of such resources and technologies to the broader research community. TMEN infrastructure is expected to establish repositories of critical reagents, resources, and information as well as promote and facilitate interdisciplinary collaborations both within and outside the Network. Mechanism of Support. This FOA will utilize the U54 cooperative agreement mechanism.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-10-021.html