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Transdisciplinary Cancer Genomics Research: Post-Genome Wide Association (Post-GWA) Initiative (U19)

Post Date

January 12th 2009

Application Due Date

May 29th 2009

Funding Opportunity Number

RFA-CA-09-002

CFDA Number(s)

93.393
93.394
93.396

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Education
Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Public and State Controlled Institutions of Higher Education
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; U.S. Territory or Possession.

Funding

  • Estimated Total Funding:

    $24000000

  • Award Range:

    $None - $3000000

Grant Description

Purpose. The purpose of this funding opportunity announcement (FOA), issued by the National Cancer Institute (NCI), is to promote thorough and efficient identification of genomic regions associated with cancer susceptibility. The FOA specifically solicits applications proposing transdisciplinary research projects designed to: a) take advantage of the existing Genome Wide Association Studies (GWAS) of cancer by exploiting previously generated initial scan GWAS data; and b) accelerate and coordinate integrative post-GWAS discovery research. To address these goals, each application should consist of two to three component sub-projects closely pertinent to a single unifying research theme. At least one of these sub-projects must address the replication or expansion of prior GWAS findings and at least one sub-project must center on epidemiologic aspects. In addition, biological and/or mechanistic studies complementing and connecting the required sub-projects are strongly encouraged as a third sub-project. The long-term goal is to provide a rigorous knowledge base that would enable clinical translation and public health dissemination of the GWAS findings. It is anticipated that these goals will require collaboration of multi-center teams comprising both epidemiologists and basic scientists.

Contact Information


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