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Center of Excellence for Natural Product Drug Interaction Research (U54)

Post Date

June 24th 2014

Application Due Date

December 4th 2014

Funding Opportunity Number

RFA-AT-15-001

CFDA Number(s)

93.213

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Number of Awards

1

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Foreign Institutions Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Funding

  • Estimated Total Funding:

    $2100000

  • Award Range:

    $None - $1400000

Grant Description

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for a Center of Excellence for Natural Product Drug Interaction Research to provide leadership in the study of natural product drug interactions. The ultimate goal of this program is to develop a definitive approach to determining the clinical relevance of pharmacokinetic interactions between natural products and medications.The Center will 1) identify, prioritize and source four to six natural products with potential to exhibit clinically significant interactions with commonly used medications; 2) work collaboratively with the NIH to develop and execute a statement of work for each of the selected natural products which will address existing gaps in the scientific literature and result in a definitive assessment regarding the clinical relevance of any pharmacokinetic interaction; 3) establish a set of best practices to address the unique challenges related to the study of natural product interactions with drugs; and 4) develop and maintain a database and public access portal for the data and methodology resources generated; thereby facilitating better design of future research and ultimately better decisions regarding the concomitant use of medications and natural products.

Contact Information


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