Development of Sample Sparing Assays for Monitoring Immune Responses (U24)

Post Date

June 2nd 2014

Application Due Date

September 26th 2014

Funding Opportunity Number

RFA-AI-14-027

CFDA Number(s)

93.242
93.855
93.856

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $5500000

• Award Range:

  $None - $400000

Grant Description

The purpose of this funding opportunity announcement (FOA) is to accelerate the development and validation of sample sparing assays that can be applied for studying the human immune system in health and disease.Development of sample sparing assays will lead to maximum use of the sampled material by significant reduction of sample volumes/amounts required or by simultaneous multi-parameter assessments of immune function.By expanding the spectrum of parameters that can be measured on small samples derived from human subjects, assays developed in response to this announcement will be valuable for advancing our fundamental understanding of the immune system and equally important for immune monitoring in healthy as well as disease conditions such as allergy, asthma, autoimmunity, acquired and primary immunodeficiency, transplantation, and infection.New sample sparing assays will have a major impact on clinical studies aimed to understand immune functions in young children with infectious diseases and/or immune mediated disorders; for example, food allergy, diabetes or primary immunodeficiency where sample availability is most limited.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-14-027.html