Immunobiology of Xenotransplantation (U01, U19)

Post Date

August 11th 2009

Application Due Date

December 2nd 2009

Funding Opportunity Number

RFA-AI-09-035

CFDA Number(s)

93.855

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $2500000

• Award Range:

  $None - $None

Grant Description

Purpose. The National Institute of Allergy and Infectious Diseases (NIAID) invites new or renewal applications to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP) for the development of pre-clinical porcine to non-human primate (NHP) models of islet, kidney, heart, lung, or liver xenotransplantation. The goals of this program are to: (1) delineate the cellular and molecular mechanisms of xenograft rejection and the induction of tolerance; (2) develop effective strategies to improve xenograft survival; and (3) characterize the physiological compatibility/limitations of xenografts. The long-term goal of this program is to develop novel and effective strategies for application of xenotransplantation in the clinic. Mechanism of Support. This FOA will use the single project (U01) and multi-project (U19) Cooperative Agreement grant mechanisms. Funds Available and Anticipated Number of Awards. The NIAID intends to commit $2.5 million total costs in FY 2010 to fund two to four new or renewal U01 and/or U19 awards in response to this FOA. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-09-035.html