Age-Related Changes in Osteoimmunology (R01)

Post Date

November 13th 2012

Application Due Date

February 7th 2013

Funding Opportunity Number

RFA-AG-13-017

CFDA Number(s)

93.866

Funding Instrument Type(s)

Grant

Funding Activity Categories

Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Funding

• Estimated Total Funding:

  $1000000

• Award Range:

  $None - $125000

Grant Description

This Funding Opportunity Announcement (FOA), issued by the National Institute on Aging (NIA) at the National Institutes of Health, solicits grant applications that propose extension of research activities on osteoimmunology in order to broaden our understanding of aging aspects of osteoimmunology, using animal models. Most studies in this field have been conducted in young mouse models (usually animals less than 6 months of age). Under those conditions, it is not possible to ascertain the effects of aging in the balance between bone metabolism and immune function. Studies sought under this FOA should focus on the impact of the age-related decline in immune function on bone homeostasis or conversely on the age-related changes in the bone marrow niche affecting the immune interactions with bone. Research in osteoimmunology aims to understand the interplay between the immune and skeletal systems, and how these interactions lead to disease when disrupted. In the clinical setting, such disequilibria and the resulting diseases are most commonly found in the elderly, which are afflicted by both immune senescence and loss of bone homeostasis. This FOA is intended as a vehicle to allow investigators already working in the field of osteoimmunology to expand the scope of their research, so as to allow an enhanced understanding of the field within the context of the clinically relevant setting of aging.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-13-017.html