Cell Lineage Determination and Tissue Homeostasis in the Aged (R01)

Post Date

June 23rd 2010

Application Due Date

October 7th 2010

Funding Opportunity Number

RFA-AG-11-001

CFDA Number(s)

93.866

Funding Instrument Type(s)

Grant

Funding Activity Categories

Health

Number of Awards

5

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $2000000

• Award Range:

  $None - $300000

Grant Description

Purpose. The National Institute on Aging (NIA), National Institutes of Health (NIH), invites Research Project Grant (R01) applications from institutions/organizations that propose to track cell lineages and to determine cell life spans in normal tissue homeostasis and in response to injury or disease in the elderly. This Funding Opportunity Announcement (FOA) will support basic and applied research projects for the determination of cell life spans and cell fates in various tissues of aged mammals, specifically in humans or in model organisms (e.g., rodents, dogs or nonhuman primates). Applications will address the quantitative analysis of cell turnover rates and cell lineage tracing in one or more cell types. Such systems should be applicable to determine the age-dependent changes in cellular turnover and fates in tissues that lose function with advanced age. Thus, applications should propose to study cell lineages and turnover in healthy aging, and may also propose to study these processes in response to acute injury or other perturbations (e.g., chronic illness). Application and submission requirements, and peer review processes will follow NIH guidelines (outlined in this FOA). Mechanism of Support. This FOA will utilize the R01 award mechanism. Funds Available and Anticipated Number of Awards. NIA budgets up to $2.0 million in Fiscal Year 2011 (FY2011) to fund up to 5 meritorious projects that are responsive to this FOA. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-11-001.html