Gut-Liver-Brain Interactions in Alcohol-Induced Pathogenesis (R21)

Post Date

December 14th 2009

Application Due Date

April 20th 2010

Funding Opportunity Number

RFA-AA-10-008

CFDA Number(s)

93.273

Funding Instrument Type(s)

Grant

Funding Activity Categories

Health

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $2000000

• Award Range:

  $None - $200000

Grant Description

Purpose. The goal of this Funding Opportunity Announcement (FOA), issued by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), is to stimulate innovative research that will determine (1) how alcohol disrupts gut-liver-brain physiological communications, and (2) how these alterations contribute to the development and exacerbation of alcohol-associated diseases. These investigations are expected to provide a more comprehensive understanding of cellular and molecular mechanisms by which alcohol impairs homeostatic functions at both organ and systemic levels and initiates/promotes tissue injury. Mechanism of Support. This FOA will utilize the NIH Exploratory/Developmental Research Grant (R21) mechanism and runs in parallel with a FOA of identical scientific scope, RFA-AA-10-007, that solicits applications under the Research Project Grant R01 mechanism. Funds Available and Anticipated Number of Awards. The NIAAA intends to commit a total of approximately $2,000,000 to this FOA and the companion RFA-AA-10-007 in FY10 to award up to 8 applications. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/rfa-files/RFA-AA-10-008.html