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Assay Development for High Throughput Molecular Screening (R21)

Post Date

April 30th 2010

Application Due Date

October 29th 2010

Funding Opportunity Number

PAR-10-182

CFDA Number(s)

93.310

Funding Instrument Type(s)

Grant

Funding Activity Categories

Health

Number of Awards

30

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

  • Estimated Total Funding:

    $6000000

  • Award Range:

    $None - $100000

Grant Description

Purpose. This FOA will facilitate the discovery of new molecular probes for investigating biological function by funding the development and adaptation of biological assays for use in automated High-Throughput Screening (HTS) projects. These HTS-ready assays can then be screened by the Molecular Libraries Production Centers Network (MLPCN) to identify biologically active compounds in a large library of small molecule chemical structures. This Program and the MLPCN are both components of the NIH Molecular Libraries and Imaging Roadmap Initiative (http://nihroadmap.nih.gov/molecularlibraries/index.asp). Mechanism of Support. This FOA will use a modified NIH Exploratory/ Developmental (R21) award mechanism. Funds Available and Anticipated Number of Awards. Approximately $6 million will be available for this FOA in 2011. This amount will be distributed in response to two due dates. NIH anticipates making approximately 30 awards in total in 2011. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received.

Contact Information


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