Countermeasures Against Chemical Threats (CounterACT) Research Centers of Excellence (U54)

Post Date

April 29th 2010

Application Due Date

September 14th 2012

Funding Opportunity Number

PAR-10-181

CFDA Number(s)

93.113
93.846
93.853
93.856
93.859
93.865
93.867

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Environment
Health
Income Security and Social Services

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Estimated Total Funding:

  $6000000

• Award Range:

  $None - $None

Grant Description

Purpose. This Funding Opportunity Announcement (FOA) encourages grant applications for Countermeasures Against Chemical Threats (CounterACT) Research Centers of Excellence (U54s). The mission of the CounterACT U54 program is to develop new and improved therapeutics for chemical threats. Chemical threats are toxic chemicals that could be used in a terrorist attack or accidentally released from industrial production, storage or shipping. They include traditional chemical warfare nerve agents such as sarin and VX, and toxic industrial chemicals and pesticides such as cyanide, chlorine, parathion, and sodium fluoroacetate. The scope of the research to be supported includes target and candidate identification and characterization, through candidate optimization and demonstration of in vivo efficacy, through Investigational New Drug (IND) submission and Phase 1 clinical trials when appropriate. Each new CounterACT Research Center of Excellence will be composed of an administrative core, scientifically related research and development subprojects, and scientific cores if needed and justified. Applicants must demonstrate that the formation of an interdisciplinary Center will produce a synergistic research environment that allows each project to share the creative strengths and resources of the others. Research and development plans must include milestones that create discrete go or no-go decision points in a progressive translational study plan. Mechanism of Support. This FOA will utilize the Specialized Center Cooperative Agreement (U54) grant mechanism and runs in parallel with a FOA of identical scientific scope, PAR-10-180 that encourages applications under the Research Project Cooperative Agreements (U01) program. Funds Available and Anticipated Number of Awards. The participating Institutes intend to commit an average of $6 million per year in Fiscal Years 2011, 2012, and 2013 to fund new and/or competing renewal awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the number, quality, duration, and costs of the applications received.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/pa-files/PAR-10-181.html