Exfoliated Cells and Circulating DNA in Cancer Detection and Diagnosis (R21)

Post Date

July 22nd 2009

Application Due Date

September 7th 2012

Funding Opportunity Number

PA-09-238

CFDA Number(s)

93.393
93.394

Funding Instrument Type(s)

Grant

Funding Activity Categories

Education
Health

Eligibility Categories

Public and State Controlled Institutions of Higher Education
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
Small Businesses
Other

Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.

Funding

• Award Range:

  $None - $200000

Grant Description

Purpose.This funding opportunity announcement (FOA), issued by the National Cancer Institute (NCI), invites applications aimed at the development of novel technologies for capturing, enriching, and preserving exfoliated abnormal cells from body fluids or effusions as well as methods for concentrating the tumor-derived sub-cellular material for use in biomarker studies. In body fluids, such as sputum, exfoliated tumor cells are a minor component compared to normal cells. As a result, the detection of exfoliated abnormal cells by routine cytopathology is often limited by the low number of atypical cells present in a given specimen. New enrichment methods are necessary to facilitate the detection of very low levels of exfoliated tumor cells and tumor-derived sub-cellular materials in biological fluids. Mechanism of Support. This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism, numbers, quality, duration, and costs of the applications received.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/pa-files/PA-09-238.html