Basic and Clinical Studies of Congenital Urinary Tract Obstruction (R01)

Post Date

July 2nd 2009

Application Due Date

September 7th 2012

Funding Opportunity Number

PA-09-226

CFDA Number(s)

93.847
93.865

Funding Instrument Type(s)

Grant

Funding Activity Categories

Food and Nutrition
Health
Income Security and Social Services

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Funding

• Award Range:

  $None - $None

Grant Description

Purpose. This Program Announcement is sponsored by the NIDDK and the NICHD. Congenital obstructive uropathy is one of the major causes of chronic kidney disease and end stage renal disease (ESRD) in infants and children. The pathogenesis of this disorder, however, remains poorly understood. Many controversies and clinical uncertainties exist in the detection, prognosis, and effective treatment strategies for this condition. The impact of early fetal detection and neonatal intervention, the long-term effects of watchful waiting and the various surgical interventions have not been well studied and documented. There is also no consensus on the indications for, or ideal timing of surgical intervention. The purpose of this funding opportunity is to address the numerous scientific and clinical uncertainties related to the development, treatment and prognosis of congenital obstructive uropathy, by encouraging and facilitating research in diverse areas. These areas include: the development of objective prognostic markers; the genetic determinants of this congenital disorder; the development of reliable animal models of the disorder; and, evaluation of the long-term effectiveness of various treatment strategies. Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) grant. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received.

Contact Information

• Agency

  Department of Health and Human Services

• Office:

  National Institutes of Health

• Agency Contact:

  NIH OER Webmaster
  FBOWebmaster@OD.NIH.GOV
  

• Agency Mailing Address:

  If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

• Agency Email Address:

  FBOWebmaster@OD.NIH.GOV

• More Information:

  http://grants.nih.gov/grants/guide/pa-files/PA-09-226.html