Stem Cells and Cancer (R21)
Post Date
May 2nd 2008
Application Due Date
May 7th 2011
Funding Opportunity Number
PA-08-165
CFDA Number(s)
93.393
93.394
93.395
93.396
93.399
Funding Instrument Type(s)
Grant
Funding Activity Categories
Eligibility Categories
State Governments
Public and State Controlled Institutions of Higher Education
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other
Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.
Funding
-
Award Range:
$None - $200000
Grant Description
Purpose. This funding opportunity announcement (FOA), issued by the National Cancer Institute (NCI), and the National Institute on Aging (NIA), encourages research in all aspects of tumor stem cell biology, including the molecular and biochemical regulation of embryonic and adult stem cell behavior relevant to tumor formation.ÊTumor stem cells are a rare population of cells that can recapitulate all the cell types represented in the original tumor. Tumor stem cells are capable of self-renewal and asymmetric cell division. These cells are putatively responsible for the transplantability and metastatic properties of tumors. This FOA intends to stimulate efforts on isolation and characterization of tumor stem cells from a large spectrum of tumors. Such studies are important in order to understand the progression of malignant diseases. They may also inspire the development of new therapeutic strategies based on specific targeting of tumor stem cells. In addition, more research is encouraged to understand the genetic and biochemical regulatory mechanisms that control the self-renewal phenotype, asymmetric cell division, and the stem cell microenvironment (or niche ).ÊIt is anticipated that the results of such research will ultimately improve the specificity and long-term effectiveness of cancer therapy.
Contact Information
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Agency
Department of Health and Human Services
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Office:
National Institutes of Health
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Agency Contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV -
Agency Mailing Address:
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
- Agency Email Address:
- More Information:
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