Host/ Gut Microbiota Response to Stressors: Informing Resiliency

Post Date

August 13th 2013

Application Due Date

November 21st 2013

Refer to the BAA/Special Notice or application instructions for white paper due dates.

Funding Opportunity Number

13-SN-0024

CFDA Number(s)

12.300

Funding Instrument Type(s)

Grant

Funding Activity Categories

Science and Technology and other Research and Development

Eligibility Categories

Unrestricted

Funding

• Award Range:

  $None - $None

Grant Description

The Office of Naval Research (ONR) is interested in receiving proposals on research directed at understanding the effects of certain behavioral and physical stressors on the host/gut microbiota, with an emphasis on deducing the role the gut microbiota (GM) may play in mediating physiological, psychological and possibly cognitive effects of such exposures. For this topic, we do not anticipate funding any human studies. Specific objectives of this Special Notice topic are: (1) To characterize the psychological, physiological and cognitive responses of the host and GM (behavior, organism, tissue and molecular levels) following exposure to various behavioral and physical stressors, such as: abnormal circadian cycles or living conditions (such as those found on a submarine), extreme/rapid environmental shifts (e.g., altitudinal, temperature, elevated ambient noise), fatigue, anticipatory anxiety or fear. (2) To ascertain if specific gut microbial community members, metabolites or functions play a role in the observed host response to the stressor(s) listed above. Comparison with data obtained for different hosts may be informative in deducing microbial functions on host response. Specific attention will be focused on тgut-brain-axisу routes of signaling. (3) Support the development of novel tools for real-time analysis of microbes, the surfaces they adhere to, and microbial products in the GI tract to more closely map microbial heterogeneity and identify specific links to their function. ************************************************************************************************************************************ The FULL ANNOUNCEMENT is available on the Grants.gov website by scrolling to the top of the synopsis page and clicking on the "FULL ANNOUNCEMENT" box surrounded by the dotted line at the top of the page.

Contact Information

• Agency

  Department of Defense

• Office:

  Office of Naval Research

• Agency Contact:

  FOR TECHNICAL QUESTIONS:
  Dr.Linda A. Chrisey
  Program Officer
  EMAIL: Linda.Chrisey@navy.mil
  
  FOR BUSINESS QUESTIONS:
  Ganesh Krish
  Contract Specialist
  EMAIL: Ganesh.Krish@navy.mil
  
  FOR TECHNICAL ISSUES WITH GRANTS.GOV:
  Please contact Grants.Gov te

• Agency Mailing Address:

  See section "Agency Contact" for details

• Agency Email Address:

  See section "Agency Contact" for details

• More Information:

  Link to all ONR Special Notices