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Human Pancreas Procurement and Analysis Program (HPPAP) (UC4)

Post Date

October 29th 2015

Application Due Date

March 3rd 2016

Funding Opportunity Number

RFA-DK-15-027

CFDA Number(s)

93.847

Funding Instrument Type(s)

Cooperative Agreement

Funding Activity Categories

Food and Nutrition
Health

Number of Awards

1

Eligibility Categories

State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Federally Recognized Native American Tribal Governments
Public Housing Authorities or Indian Housing Authorities
Non-Federally Recognized Native American Tribal Organizations
Non-Profits With 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Non-Profits Without 501 (c) (3) Status With The IRS (Except Higher Education Institutions)
Private Institutions of Higher Education
For-Profit Organizations (Except Small Businesses)
Small Businesses
Other

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Funding

  • Estimated Total Funding:

    $15000000

  • Award Range:

    $None - $2300000

Grant Description

This Funding Opportunity Announcement (FOA) invites cooperative agreement applications to develop and operate a Human Pancreas Procurement and Analysis Program (HPPAP). This FOA will support the assembly of a team of investigators with combined expertise in human pancreas physiology and pathophysiology; collection, analysis and distribution of human pancreatic tissues; and analysis and integration of complex biological datasets, that will be tasked to: 1) collect and intensively characterize primary pancreatic tissues from patients with T1D, pre-T1D (i.e. positive for multiple islet autoantibodies) or rare forms of islet dysfunction, 2) distribute these specimens and their extensive linked data to the larger research community for expanded analysis, and 3) organize the data collected from the study of these tissues into an open-access resource database (PANC DB). HPPAP will become a component of the Human Islet Research Network (HIRN) created in 2014 to support innovative and collaborative translational research to understand how human beta cells are lost in T1D, and to find innovative strategies to protect and replace functional human beta cell mass.

Contact Information


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